CAPN7

GENE INFORMATION

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Gene name

CAPN7 (HGNC Symbol)

Synonyms

PalBH

Description

calpain 7 (HGNC Symbol)

Entrez gene summary

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

p25.1

Chromosome location (bp)

15247659 - 15294425

Ensembl

ENSG00000131375 (version 73.37)

Entrez gene

23473

UniProt

Q9Y6W3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6W3

Antibodypedia

CAPN7 antibodies
 

PROTEIN VIEW

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CAPN7-001
 
CAPN7-004
 
CAPN7-005
 
CAPN7-006
 
CAPN7-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CAPN7-001 ENSP00000253693
ENST00000253693
Q9Y6W3
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Show » Show » 813 92.7 No 0
CAPN7-004 ENSP00000415482
ENST00000418994
F8WCZ1
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36 4.2 No 0
CAPN7-005 ENSP00000389786
ENST00000457023
F8WDQ3
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42 5 No 0
CAPN7-006 ENSP00000399486
ENST00000415565
Show » 248 28.5 No 0
CAPN7-007 ENSP00000394708
ENST00000443567
H7C0F1
Show all »
Show » 112 13.7 No 0