AOC3

GENE INFORMATION

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Gene name

AOC3 (HGNC Symbol)

Synonyms

HPAO, VAP-1, VAP1

Description

amine oxidase, copper containing 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

Chromosome

17 (Chromosome progress)

Cytoband

q21.31

Chromosome location (bp)

41003201 - 41010147

Ensembl

ENSG00000131471 (version 73.37)

Entrez gene

8639

UniProt

Q16853 (UniProt - Evidence at protein level)

neXtProt

NX_Q16853

Antibodypedia

AOC3 antibodies
 

PROTEIN VIEW

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AOC3-001
 
AOC3-002
 
AOC3-003
 
AOC3-004
 
AOC3-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AOC3-001 ENSP00000312326
ENST00000308423
Q16853
Show all »
Show » Show » 763 84.6 Yes 0
AOC3-002 ENSP00000468632
ENST00000591562
K7ESB3
Show all »
Show » 220 24.5 No 0
AOC3-003 ENSP00000464787
ENST00000587330
Show » Show » 144 15.1 No 0
AOC3-004 ENSP00000465913
ENST00000592999
K7EL47
Show all »
Show » 152 17.3 No 0
AOC3-005 ENSP00000468043
ENST00000588033
K7EQZ5
Show all »
Show » 112 12.9 No 0