The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Most normal tissues displayed moderate cytoplasmic positivity, often combined with nuclear staining. Strong staining was observed in prostate, testis and islets of Langerhans. Smooth muscle cells were negative.
Most normal tissues displayed moderate cytoplasmic positivity. Strong staining was observed in pancreatic islet cells and Leydig cells. Glial cells, smooth muscle, most squamous epithelial cells, ovarian and endometrial stromal cells were negative.
Most normal tissues showed weak cytoplasmic and nuclear positivity or were negative. Strong staining was observed in islets of Langerhans, the prostate, Leydig cells and subsets of cells in seminiferous ducts.
Weak to moderate cytoplasmic staining often combined with nuclear positivity was observed in most normal tissues. Leydig cells, purkinje cells and most squamous epithelia were strongly stained. Liver and glial cells were negative.
Strong cytoplasmic and nuclear staining was observed in the majority of normal tissues. Hepatocytes and smooth muscle cells were negative.