RBM8A

GENE INFORMATION

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Gene name

RBM8A (HGNC Symbol)

Synonyms

BOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP

Description

RNA binding motif protein 8A (HGNC Symbol)

Entrez gene summary

This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]

Chromosome

1 (Chromosome progress)

Cytoband

q21.1

Chromosome location (bp)

145507598 - 145511444

Ensembl

ENSG00000131795 (version 73.37)

Entrez gene

9939

UniProt

Q9Y5S9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5S9

Antibodypedia

RBM8A antibodies
 

PROTEIN VIEW

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RBM8A-001
 
RBM8A-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RBM8A-001 ENSP00000333001
ENST00000330165
Q9Y5S9
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Show » Show » 174 19.9 No 0
RBM8A-002 ENSP00000358313
ENST00000369307
Q9Y5S9
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Show » Show » 173 19.8 No 0