VIMP

GENE INFORMATION

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Gene name

VIMP (HGNC Symbol)

Synonyms

AD-015, MGC2553, SBBI8, SELS, SEPS1

Description

VCP-interacting membrane protein (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the selenoprotein family, characterized by a selenocysteine (Sec) residue at the active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]

Chromosome

15 (Chromosome progress)

Cytoband

q26.3

Chromosome location (bp)

101811022 - 101817705

Ensembl

ENSG00000131871 (version 73.37)

Entrez gene

55829

UniProt

Q9BQE4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BQE4

Antibodypedia

VIMP antibodies
 

PROTEIN VIEW

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VIMP-001
 
VIMP-002
 
VIMP-005
 
VIMP-006
 
VIMP-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VIMP-001 ENSP00000381282
ENST00000398226
Q9BQE4
Show all »
Show » Show » 189 21.2 No 1
VIMP-002 ENSP00000433541
ENST00000526049
Q9BQE4
Show all »
Show » Show » 189 21.2 No 1
VIMP-005 ENSP00000433803
ENST00000531964
Show » Show » 166 18.5 No 1
VIMP-006 ENSP00000434842
ENST00000528346
E9PN30
Show all »
Show » Show » 218 23.8 No 1
VIMP-201 ENSP00000437381
ENST00000537379
Q6GYA4
Show all »
Show » Show » 187 21 No 1