ABHD12B

GENE INFORMATION

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Gene name

ABHD12B (HGNC Symbol)

Synonyms

BEM46L3, C14orf29

Description

Abhydrolase domain containing 12B (HGNC Symbol)

Entrez gene summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Chromosome

14

Cytoband

q22.1

Chromosome location (bp)

51338878 - 51371688

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131969 (version 75.37)

Entrez gene

100616234

UniProt

Q7Z5M8 (UniProt - Evidence at transcript level)

neXtProt

NX_Q7Z5M8

Antibodypedia

ABHD12B antibodies
 

PROTEIN VIEW

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ABHD12B-001
 
ABHD12B-002
 
ABHD12B-003
 
ABHD12B-004
 
ABHD12B-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABHD12B-001 ENSP00000343951
ENST00000353130
Q7Z5M8
Show all »
Show » 285 31.8 No 0
ABHD12B-002 ENSP00000371460
ENST00000382029
Q7Z5M8
Show all »
Show » 60 6.6 No 0
ABHD12B-003 ENSP00000336693
ENST00000337334
Q7Z5M8
Show all »
Show » Show » 362 40.8 No 0
ABHD12B-004 ENSP00000450643
ENST00000557345
Q7Z5M8
Show all »
Show » 60 6.6 No 0
ABHD12B-201 ENSP00000379101
ENST00000395752
Q7Z5M8
Show all »
Show » 255 28.6 No 0