TRIM22

GENE INFORMATION

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Gene name

TRIM22 (HGNC Symbol)

Synonyms

GPSTAF50, RNF94, STAF50

Description

tripartite motif containing 22 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Chromosome

11 (Chromosome progress)

Cytoband

p15.4

Chromosome location (bp)

5710919 - 5758319

Ensembl

ENSG00000132274 (version 73.37)

Entrez gene

10346

UniProt

Q8IYM9 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IYM9

Antibodypedia

TRIM22 antibodies
 

PROTEIN VIEW

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TRIM22-001
 
TRIM22-003
 
TRIM22-005
 
TRIM22-006
 
TRIM22-007
 
TRIM22-008
 
TRIM22-010
 
TRIM22-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRIM22-001 ENSP00000369299
ENST00000379965
Q8IYM9
Show all »
Show » 498 56.9 No 0
TRIM22-003 ENSP00000400417
ENST00000425490
C9J060
Show all »
Show » 203 23.7 No 0
TRIM22-005 ENSP00000396849
ENST00000414641
C9JIU5
Show all »
Show » 227 26.3 No 0
TRIM22-006 ENSP00000393250
ENST00000454828
C9JWC5
Show all »
Show » 305 34.9 No 0
TRIM22-007 ENSP00000388994
ENST00000414897
Show » 143 16.7 No 0
TRIM22-008 ENSP00000406412
ENST00000450670
H7C2K0
Show all »
63 7.6 No 0
TRIM22-010 ENSP00000409991
ENST00000429063
37 4.3 No 0
TRIM22-011 ENSP00000404204
ENST00000444844
38 4.4 No 0