MRPL35

GENE INFORMATION

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Gene name

MRPL35

Synonyms

Description

mitochondrial ribosomal protein L35 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p, 10q, and Xp. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

p11.2

Chromosome location (bp)

86426478 - 86440917

Ensembl

ENSG00000132313 (version 73.37)

Entrez gene

51318

UniProt

Q9NZE8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NZE8

Antibodypedia

MRPL35 antibodies
 

PROTEIN VIEW

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MRPL35-001
 
MRPL35-002
 
MRPL35-003
 
MRPL35-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL35-001 ENSP00000338389
ENST00000337109
Q9NZE8
Show all »
Show » Show » 188 21.5 No 0
MRPL35-002 ENSP00000254644
ENST00000254644
Q9NZE8
Show all »
Show » Show » 170 19.2 Yes 0
MRPL35-003 ENSP00000386255
ENST00000409180
D3YTC1
Show all »
Show » 177 20.1 Yes 0
MRPL35-004 ENSP00000473925
ENST00000605125
95 10.2 No 0