SNAP25

GENE INFORMATION

? »

Gene name

SNAP25 (HGNC Symbol)

Synonyms

bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25

Description

synaptosomal-associated protein, 25kDa (HGNC Symbol)

Entrez gene summary

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

20 (Chromosome progress)

Cytoband

p12.2

Chromosome location (bp)

10199478 - 10288066

Ensembl

ENSG00000132639 (version 73.37)

Entrez gene

6616

UniProt

P60880 (UniProt - Evidence at protein level)

neXtProt

NX_P60880

Antibodypedia

SNAP25 antibodies
 

PROTEIN VIEW

? »
 
 
 
SNAP25-002
 
SNAP25-003
 
SNAP25-004
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNAP25-002 ENSP00000400720
ENST00000430336
P60880
Show all »
Show » Show » 93 10.7 No 0
SNAP25-003 ENSP00000254976
ENST00000254976
P60880
Show all »
Show » Show » 206 23.3 No 0
SNAP25-004 ENSP00000307341
ENST00000304886
P60880
Show all »
Show » Show » 206 23.3 No 0