ATP1A4

GENE INFORMATION

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Gene name

ATP1A4 (HGNC Symbol)

Synonyms

ATP1AL2

Description

ATPase, Na+/K+ transporting, alpha 4 polypeptide (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q23.2

Chromosome location (bp)

160121360 - 160156767

Ensembl

ENSG00000132681 (version 73.37)

Entrez gene

480

UniProt

Q13733 (UniProt - Evidence at protein level)

neXtProt

NX_Q13733

Antibodypedia

ATP1A4 antibodies
 

PROTEIN VIEW

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ATP1A4-001
 
ATP1A4-004
 
ATP1A4-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP1A4-001 ENSP00000357060
ENST00000368081
Q13733
Show all »
Show » Show » 1029 114.2 No >9
ATP1A4-004 ENSP00000434272
ENST00000477338
E9PRA5
Show all »
Show » Show » 517 57.2 No 4
ATP1A4-006 ENSP00000433094
ENST00000470705
Q13733
Show all »
Show » Show » 165 19.6 No 3