APCS

GENE INFORMATION

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Gene name

APCS (HGNC Symbol)

Synonyms

MGC88159, PTX2, SAP

Description

amyloid P component, serum (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q23.2

Chromosome location (bp)

159557615 - 159558655

Ensembl

ENSG00000132703 (version 73.37)

Entrez gene

325

UniProt

P02743 (UniProt - Evidence at protein level)

neXtProt

NX_P02743

Antibodypedia

APCS antibodies
 

PROTEIN VIEW

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APCS-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APCS-001 ENSP00000255040
ENST00000255040
P02743
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