WASF3

GENERAL INFORMATION

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Gene name

WASF3

Gene description

WAS protein family, member 3

Protein class

Cancer-related genes
Cytoskeleton related proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (cerebral cortex)
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
CAB037086
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

WASF3 (HGNC Symbol)

Synonyms

KIAA0900, SCAR3, WAVE3

Description

WAS protein family, member 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014]

Chromosome

13

Cytoband

q12.13

Chromosome location (bp)

26557703 - 26688948

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000132970 (version 78.38)

Entrez gene

10810

UniProt

Q9UPY6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UPY6

Antibodypedia

WASF3 antibodies


PROTEIN BROWSER

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ENST00000335327
 
ENST00000361042
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WASF3-001 ENSP00000335055
ENST00000335327
Q9UPY6
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Show » Show » 502 55.3 No 0
WASF3-201 ENSP00000354325
ENST00000361042
Q9UPY6
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Show » Show » 499 55 No 0