TRPC4

GENE INFORMATION

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Gene name

TRPC4 (HGNC Symbol)

Synonyms

HTRP4, TRP4

Description

transient receptor potential cation channel, subfamily C, member 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

Chromosome

13 (Chromosome progress)

Cytoband

q13.3

Chromosome location (bp)

38210773 - 38444562

Ensembl

ENSG00000133107 (version 73.37)

Entrez gene

7223

UniProt

Q9UBN4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UBN4

Antibodypedia

TRPC4 antibodies
 

PROTEIN VIEW

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TRPC4-001
 
TRPC4-002
 
TRPC4-003
 
TRPC4-004
 
TRPC4-005
 
TRPC4-006
 
TRPC4-201
 
TRPC4-202
 
TRPC4-203
 
TRPC4-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRPC4-001 ENSP00000369027
ENST00000379705
Q9UBN4
Show all »
Show » Show » 977 112.1 No 8
TRPC4-002 ENSP00000348025
ENST00000355779
Q9UBN4
Show all »
Show » Show » 836 96.4 No 8
TRPC4-003 ENSP00000351264
ENST00000358477
Q9UBN4
Show all »
Show » Show » 893 102.6 No 8
TRPC4-004 ENSP00000368995
ENST00000379673
Q9UBN4
Show all »
Show » Show » 828 94.9 No 8
TRPC4-005 ENSP00000435969
ENST00000488717
Q96P04
Show all »
Show » 323 36.8 No 0
TRPC4-006 ENSP00000369001
ENST00000379679
Q9UBN4
Show all »
Show » Show » 804 92.2 No 8
TRPC4-201 ENSP00000342580
ENST00000338947
Q9UBN4
Show all »
Show » Show » 804 92.2 No 8
TRPC4-202 ENSP00000369003
ENST00000379681
Q9UBN4
Show all »
Show » Show » 982 112.7 No 8
TRPC4-203 ENSP00000410133
ENST00000426868
Q3MHB9
Show all »
Show » Show » 460 53.1 No 4
TRPC4-204 ENSP00000414316
ENST00000447043
Q9UBN4
Show all »
Show » Show » 836 96.4 No 8