KL

GENE INFORMATION

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Gene name

KL

Synonyms

Description

klotho (HGNC Symbol)

Entrez gene summary

This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008]

Chromosome

13 (Chromosome progress)

Cytoband

q13.1

Chromosome location (bp)

33590207 - 33640282

Ensembl

ENSG00000133116 (version 73.37)

Entrez gene

9365

UniProt

Q9UEF7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UEF7

Antibodypedia

KL antibodies
 

PROTEIN VIEW

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KL-001
 
KL-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KL-001 ENSP00000369442
ENST00000380099
Q9UEF7
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Show » Show » 1012 116.2 Yes 1
KL-201 ENSP00000399513
ENST00000426690
B3KUJ4
Show all »
Show » 242 28.1 No 0