BEX2

GENE INFORMATION

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Gene name

BEX2 (HGNC Symbol)

Synonyms

DJ79P11.1

Description

Brain expressed X-linked 2 (HGNC Symbol)

Entrez gene summary

This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Chromosome

X

Cytoband

q22.1

Chromosome location (bp)

102564274 - 102565974

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133134 (version 75.37)

Entrez gene

84707

UniProt

Q9BXY8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BXY8

Antibodypedia

BEX2 antibodies
 

PROTEIN VIEW

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BEX2-001
 
BEX2-002
 
BEX2-003
 
BEX2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BEX2-001 ENSP00000394915
ENST00000449185
101 12.2 No 0
BEX2-002 ENSP00000361762
ENST00000372677
Q9BXY8
Show all »
Show » 128 15.3 No 0
BEX2-003 ENSP00000361759
ENST00000372674
Q9BXY8
Show all »
Show » 128 15.3 No 0
BEX2-201 ENSP00000442521
ENST00000536889
Q9BXY8
Show all »
Show » 160 18.7 No 0