BEX2

GENERAL INFORMATION

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Gene name

BEX2

Gene description

Brain expressed X-linked 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in most cell types.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.

Data reliability

Uncertain based on 1 antibody.
HPA045384
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Thyroid gland

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

BEX2 (HGNC Symbol)

Synonyms

DJ79P11.1

Description

Brain expressed X-linked 2 (HGNC Symbol)

Entrez gene summary

This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Chromosome

X

Cytoband

q22.2

Chromosome location (bp)

103309346 - 103311046

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133134 (version 78.38)

Entrez gene

84707

UniProt

Q9BXY8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BXY8

Antibodypedia

BEX2 antibodies


PROTEIN BROWSER

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ENST00000372674
 
ENST00000372677
 
ENST00000449185
 
ENST00000536889
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BEX2-001 ENSP00000394915
ENST00000449185
X6RDN0
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Show » 101 12.2 No 0
BEX2-002 ENSP00000361762
ENST00000372677
Q9BXY8
Show all »
Show » Show » 128 15.3 No 0
BEX2-003 ENSP00000361759
ENST00000372674
Q9BXY8
Show all »
Show » Show » 128 15.3 No 0
BEX2-201 ENSP00000442521
ENST00000536889
Q9BXY8
Show all »
Show » Show » 160 18.7 No 0