EPHB2

GENE INFORMATION

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Gene name

EPHB2 (HGNC Symbol)

Synonyms

DRT, EPHT3, ERK, Hek5, Tyro5

Description

EPH receptor B2 (HGNC Symbol)

Entrez gene summary

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p36.12

Chromosome location (bp)

23037332 - 23241818

Ensembl

ENSG00000133216 (version 73.37)

Entrez gene

2048

UniProt

P29323 (UniProt - Evidence at protein level)

neXtProt

NX_P29323

Antibodypedia

EPHB2 antibodies
 

PROTEIN VIEW

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EPHB2-001
 
EPHB2-002
 
EPHB2-003
 
EPHB2-004
 
EPHB2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHB2-001 ENSP00000383053
ENST00000400191
P29323
Show all »
Show » Show » 1055 117.5 Yes 2
EPHB2-002 ENSP00000363763
ENST00000374632
P29323
Show all »
Show » Show » 987 110 Yes 2
EPHB2-003 ENSP00000363761
ENST00000374630
P29323
Show all »
Show » Show » 986 109.9 Yes 2
EPHB2-004 ENSP00000363758
ENST00000374627
B1AKC9
Show all »
Show » Show » 946 105.6 No 2
EPHB2-201 ENSP00000444174
ENST00000544305
Q6NVW1
Show all »
Show » Show » 482 53.3 Yes 0