GGT2

GENE INFORMATION

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Gene name

GGT2 (HGNC Symbol)

Synonyms

GGT

Description

gamma-glutamyltransferase 2 (HGNC Symbol)

Entrez gene summary

GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]

Chromosome

22 (Chromosome progress)

Cytoband

q11.21

Chromosome location (bp)

21562262 - 21581926

Ensembl

ENSG00000133475 (version 73.37)

Entrez gene

728441

UniProt

P36268 (UniProt - Evidence at protein level)

neXtProt

NX_P36268

Antibodypedia

GGT2 antibodies
 

PROTEIN VIEW

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GGT2-001
 
GGT2-002
 
GGT2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GGT2-001 ENSP00000385601
ENST00000405188
B5MCK8
Show all »
Show » Show » 559 60.9 Yes 1
GGT2-002 ENSP00000385721
ENST00000401924
P36268
Show all »
Show » Show » 569 61.8 Yes 1
GGT2-201 ENSP00000402035
ENST00000424627
P36268
Show all »
Show » Show » 569 61.8 Yes 1