CA1

GENE INFORMATION

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Gene name

CA1 (HGNC Symbol)

Synonyms

Car1

Description

carbonic anhydrase I (HGNC Symbol)

Entrez gene summary

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature. [provided by RefSeq, Sep 2009]

Chromosome

8 (Chromosome progress)

Cytoband

q21.2

Chromosome location (bp)

86239837 - 86291243

Ensembl

ENSG00000133742 (version 73.37)

Entrez gene

759

UniProt

P00915 (UniProt - Evidence at protein level)

neXtProt

NX_P00915

Antibodypedia

CA1 antibodies
 

PROTEIN VIEW

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 « 
 
CA1-001
 
CA1-003
 
CA1-004
 
CA1-005
 
CA1-006
 
CA1-007
 
CA1-010
 
CA1-011
 
CA1-013
 
CA1-014
 
CA1-015
 
CA1-017
 
CA1-019
 
CA1-020
 
CA1-021
 
CA1-022
 
CA1-201
 
CA1-202
 
CA1-203
 
CA1-204
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CA1-001 ENSP00000430656
ENST00000523953
P00915
Show all »
Show » Show » 261 28.9 No 0
CA1-003 ENSP00000429798
ENST00000523022
P00915
Show all »
Show » Show » 261 28.9 No 0
CA1-004 ENSP00000430471
ENST00000521846
E5RG43
Show all »
Show » 149 16.4 No 0
CA1-005 ENSP00000430975
ENST00000523858
E5RGU8
Show all »
Show » 99 11.2 No 0
CA1-006 ENSP00000427852
ENST00000522579
E5RG43
Show all »
Show » 149 16.4 No 0
CA1-007 ENSP00000429688
ENST00000519129
E5RHS7
Show all »
22 2.6 No 0
CA1-010 ENSP00000429843
ENST00000517590
E5RH81
Show all »
Show » 176 19.3 No 0
CA1-011 ENSP00000430571
ENST00000520663
E5RJF6
Show all »
Show » 87 9.4 No 0
CA1-013 ENSP00000430737
ENST00000522814
E5RIF9
Show all »
Show » 148 16.3 No 0
CA1-014 ENSP00000430372
ENST00000522662
E5RFL2
Show all »
Show » 118 13.3 No 0
CA1-015 ENSP00000430861
ENST00000517618
E5RHP7
Show all »
Show » 251 27.8 No 0
CA1-017 ENSP00000430710
ENST00000517429
E5RII2
Show all »
Show » 81 9 No 0
CA1-019 ENSP00000430543
ENST00000519991
E5RJI8
Show all »
Show » 138 15.1 No 0
CA1-020 ENSP00000427773
ENST00000522389
E5RG81
Show all »
Show » 127 14 No 0
CA1-021 ENSP00000428923
ENST00000524324
E5RFE7
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Show » 194 21.4 No 0
CA1-022 ENSP00000429300
ENST00000521679
178 19.7 No 0
CA1-201 ENSP00000256119
ENST00000256119
P00915
Show all »
Show » Show » 261 28.9 No 0
CA1-202 ENSP00000392338
ENST00000431316
P00915
Show all »
Show » Show » 261 28.9 No 0
CA1-203 ENSP00000401551
ENST00000432364
P00915
Show all »
Show » Show » 261 28.9 No 0
CA1-204 ENSP00000443517
ENST00000542576
P00915
Show all »
Show » Show » 261 28.9 No 0