ARNTL

GENE INFORMATION

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Gene name

ARNTL (HGNC Symbol)

Synonyms

bHLHe5, BMAL1, JAP3, MOP3, PASD3

Description

Aryl hydrocarbon receptor nuclear translocator-like (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]

Chromosome

11

Cytoband

p15.2

Chromosome location (bp)

13298199 - 13408813

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133794 (version 75.37)

Entrez gene

406

UniProt

O00327 (UniProt - Evidence at protein level)

neXtProt

NX_O00327

Antibodypedia

ARNTL antibodies
 

PROTEIN VIEW

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ARNTL-001
 
ARNTL-002
 
ARNTL-003
 
ARNTL-004
 
ARNTL-005
 
ARNTL-008
 
ARNTL-011
 
ARNTL-014
 
ARNTL-015
 
ARNTL-016
 
ARNTL-017
 
ARNTL-018
 
ARNTL-019
 
ARNTL-020
 
ARNTL-022
 
ARNTL-201
 
ARNTL-202
 
ARNTL-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARNTL-001 ENSP00000374357
ENST00000389707
O00327
Show all »
Show » Show » 625 68.7 No 0
ARNTL-002 ENSP00000385581
ENST00000403510
O00327
Show all »
Show » Show » 582 64.1 No 0
ARNTL-003 ENSP00000385915
ENST00000401424
O00327
Show all »
Show » Show » 583 64.2 No 0
ARNTL-004 ENSP00000384517
ENST00000403290
O00327
Show all »
Show » Show » 626 68.8 No 0
ARNTL-005 ENSP00000385897
ENST00000403482
O00327
Show all »
Show » Show » 624 68.8 Yes 0
ARNTL-008 ENSP00000436721
ENST00000482049
E9PI92
Show all »
Show » Show » 72 8.4 No 0
ARNTL-011 ENSP00000434781
ENST00000531665
E9PNI4
Show all »
Show » Show » 61 6.7 No 0
ARNTL-014 ENSP00000436442
ENST00000524392
H0YER9
Show all »
Show » Show » 171 19.4 No 0
ARNTL-015 ENSP00000431566
ENST00000534544
E9PKN1
Show all »
Show » Show » 59 6.4 No 0
ARNTL-016 ENSP00000434044
ENST00000529050
E9PSD2
Show all »
Show » Show » 23 2.5 No 0
ARNTL-017 ENSP00000434263
ENST00000529825
E9PRB1
Show all »
Show » Show » 46 5.6 No 0
ARNTL-018 ENSP00000436313
ENST00000530357
E9PPV4
Show all »
Show » Show » 141 16.2 No 0
ARNTL-019 ENSP00000433540
ENST00000527998
E9PKG7
Show all »
Show » Show » 76 8.4 No 0
ARNTL-020 ENSP00000431488
ENST00000533520
E9PL54
Show all »
Show » Show » 101 11.4 No 0
ARNTL-022 ENSP00000433571
ENST00000529388
E9PKF0
Show all »
Show » Show » 135 15.2 No 0
ARNTL-201 ENSP00000354278
ENST00000361003
O00327
Show all »
Show » Show » 508 55.5 No 0
ARNTL-202 ENSP00000374358
ENST00000389708
F8W6J9
Show all »
Show » Show » 526 59.3 No 0
ARNTL-203 ENSP00000379718
ENST00000396441
O00327
Show all »
Show » Show » 625 68.7 No 0