HSD17B4

GENE INFORMATION

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Gene name

HSD17B4 (HGNC Symbol)

Synonyms

DBP, MFE-2, SDR8C1

Description

hydroxysteroid (17-beta) dehydrogenase 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q23.1

Chromosome location (bp)

118788138 - 118972894

Ensembl

ENSG00000133835 (version 73.37)

Entrez gene

3295

UniProt

P51659 (UniProt - Evidence at protein level)

neXtProt

NX_P51659

Antibodypedia

HSD17B4 antibodies
 

PROTEIN VIEW

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HSD17B4-001
 
HSD17B4-002
 
HSD17B4-003
 
HSD17B4-004
 
HSD17B4-005
 
HSD17B4-006
 
HSD17B4-007
 
HSD17B4-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSD17B4-001 ENSP00000256216
ENST00000256216
P51659
Show all »
Show » Show » 736 79.7 No 0
HSD17B4-002 ENSP00000424613
ENST00000515320
P51659
Show all »
Show » Show » 718 77.9 No 0
HSD17B4-003 ENSP00000420914
ENST00000504811
P51659
Show all »
Show » Show » 761 83 No 0
HSD17B4-004 ENSP00000411960
ENST00000414835
G5E9S2
Show all »
Show » 596 64.6 No 0
HSD17B4-005 ENSP00000424940
ENST00000510025
E7EWE5
Show all »
Show » Show » 712 77.6 No 0
HSD17B4-006 ENSP00000426272
ENST00000509514
E7EPL9
Show all »
Show » 474 51 No 0
HSD17B4-007 ENSP00000425993
ENST00000513628
E7ET17
Show all »
Show » Show » 599 65 No 0
HSD17B4-009 ENSP00000390208
ENST00000442060
E7ER27
Show all »
Show » 500 53.9 No 0