CDK7

GENE INFORMATION

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Gene name

CDK7 (HGNC Symbol)

Synonyms

CAK, CAK1, CDKN7, MO15, STK1

Description

cyclin-dependent kinase 7 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q13.2

Chromosome location (bp)

68530668 - 68573250

Ensembl

ENSG00000134058 (version 73.37)

Entrez gene

1022

UniProt

P50613 (UniProt - Evidence at protein level)

neXtProt

NX_P50613

Antibodypedia

CDK7 antibodies
 

PROTEIN VIEW

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CDK7-001
 
CDK7-003
 
CDK7-004
 
CDK7-005
 
CDK7-006
 
CDK7-007
 
CDK7-009
 
CDK7-010
 
CDK7-011
 
CDK7-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDK7-001 ENSP00000256443
ENST00000256443
P50613
Show all »
Show » Show » 346 39 No 0
CDK7-003 ENSP00000422121
ENST00000502604
D6R9G1
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Show » Show » 253 28.5 No 0
CDK7-004 ENSP00000422737
ENST00000514676
D6RAD4
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Show » Show » 309 34.6 No 0
CDK7-005 ENSP00000425043
ENST00000506563
D6REC6
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Show » Show » 149 17 No 0
CDK7-006 ENSP00000425893
ENST00000515391
D6RIG9
Show all »
Show » 77 8.8 No 0
CDK7-007 ENSP00000426372
ENST00000515180
D6RGG9
Show all »
Show » 55 6.2 No 0
CDK7-009 ENSP00000422027
ENST00000504147
D6R9Z2
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Show » 58 6.5 No 0
CDK7-010 ENSP00000425983
ENST00000506789
D6RI01
Show all »
Show » 58 6.6 No 0
CDK7-011 ENSP00000426561
ENST00000510106
D6RFL0
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Show » 43 4.9 No 0
CDK7-013 ENSP00000421559
ENST00000508726
D6RF14
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Show » 69 7.7 No 0