CD180

GENE INFORMATION

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Gene name

CD180 (HGNC Symbol)

Synonyms

LY64, Ly78, RP105

Description

CD180 molecule (HGNC Symbol)

Entrez gene summary

CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q12.3

Chromosome location (bp)

66478103 - 66492627

Ensembl

ENSG00000134061 (version 73.37)

Entrez gene

4064

UniProt

Q99467 (UniProt - Evidence at protein level)

neXtProt

NX_Q99467

Antibodypedia

CD180 antibodies
 

PROTEIN VIEW

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CD180-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD180-001 ENSP00000256447
ENST00000256447
Q99467
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