TRPM1

GENE INFORMATION

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Gene name

TRPM1 (HGNC Symbol)

Synonyms

LTRPC1, MLSN1

Description

transient receptor potential cation channel, subfamily M, member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

Chromosome

15 (Chromosome progress)

Cytoband

q13.3

Chromosome location (bp)

31293264 - 31453476

Ensembl

ENSG00000134160 (version 73.37)

Entrez gene

4308

UniProt

Q7Z4N2 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z4N2

Antibodypedia

TRPM1 antibodies
 

PROTEIN VIEW

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TRPM1-001
 
TRPM1-002
 
TRPM1-003
 
TRPM1-004
 
TRPM1-005
 
TRPM1-006
 
TRPM1-007
 
TRPM1-008
 
TRPM1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRPM1-001 ENSP00000380897
ENST00000397795
Q7Z4N2
Show all »
Show » Show » 1603 182.2 No 8
TRPM1-002 ENSP00000453477
ENST00000559177
H0YM61
Show all »
Show » 505 57.4 No 2
TRPM1-003 ENSP00000453851
ENST00000559179
Q7Z4N2
Show all »
Show » Show » 136 15.1 No 0
TRPM1-004 ENSP00000256552
ENST00000256552
Q7Z4N2
Show all »
Show » Show » 1625 184.8 No 7
TRPM1-005 ENSP00000454077
ENST00000560658
Q7Z4N2
Show all »
Show » Show » 300 32.8 No 0
TRPM1-006 ENSP00000453644
ENST00000560801
Q7Z4N2
Show all »
Show » Show » 230 25.1 No 0
TRPM1-007 ENSP00000453119
ENST00000558768
Q7Z4N2
Show all »
Show » Show » 1527 173.8 No 7
TRPM1-008 ENSP00000452946
ENST00000558445
H0YKU7
Show all »
Show » Show » 1390 158.4 No 8
TRPM1-201 ENSP00000437849
ENST00000542188
Q7Z4N2
Show all »
Show » Show » 1642 186.5 No 8