VAV3

GENE INFORMATION

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Gene name

VAV3

Synonyms

Description

vav 3 guanine nucleotide exchange factor (HGNC Symbol)

Entrez gene summary

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

108113782 - 108507766

Ensembl

ENSG00000134215 (version 73.37)

Entrez gene

10451

UniProt

Q9UKW4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKW4

Antibodypedia

VAV3 antibodies
 

PROTEIN VIEW

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VAV3-001
 
VAV3-005
 
VAV3-006
 
VAV3-007
 
VAV3-009
 
VAV3-012
 
VAV3-016
 
VAV3-201
 
VAV3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VAV3-001 ENSP00000359073
ENST00000370056
Q9UKW4
Show all »
Show » Show » 847 97.8 No 0
VAV3-005 ENSP00000394897
ENST00000415432
Q9UKW4
Show all »
Show » Show » 287 32.6 No 0
VAV3-006 ENSP00000433559
ENST00000490388
H9KV67
Show all »
Show » 616 71.4 No 0
VAV3-007 ENSP00000432540
ENST00000527011
Q9UKW4
Show all »
Show » Show » 875 100.8 No 0
VAV3-009 ENSP00000432865
ENST00000529413
E9PMJ5
Show all »
52 6 No 0
VAV3-012 ENSP00000431544
ENST00000529809
Show » Show » 182 20.5 No 0
VAV3-016 ENSP00000434944
ENST00000525231
E9PMJ5
Show all »
52 6 No 0
VAV3-201 ENSP00000360912
ENST00000371846
H9KV67
Show all »
Show » 556 64.6 No 0
VAV3-202 ENSP00000446404
ENST00000544443
F5GXH7
Show all »
Show » Show » 251 28.5 No 0