PSRC1

GENE INFORMATION

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Gene name

PSRC1 (HGNC Symbol)

Synonyms

DDA3

Description

proline/serine-rich coiled-coil 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a proline-rich protein. Studies of this gene and the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. The encoded protein may function as a microtubule destabilizing protein that controls spindle dynamics and mitotic progression by recruiting and regulating microtubule depolymerases. At least one genetic variation in this gene has been associated with decreased serum levels of low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2009]

Chromosome

1 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

109822178 - 109825808

Ensembl

ENSG00000134222 (version 73.37)

Entrez gene

84722

UniProt

Q6PGN9 (UniProt - Evidence at protein level)

neXtProt

NX_Q6PGN9

Antibodypedia

PSRC1 antibodies
 

PROTEIN VIEW

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PSRC1-001
 
PSRC1-002
 
PSRC1-003
 
PSRC1-005
 
PSRC1-006
 
PSRC1-007
 
PSRC1-009
 
PSRC1-010
 
PSRC1-201
 
PSRC1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSRC1-001 ENSP00000358923
ENST00000369907
Q6PGN9
Show all »
Show » 333 35.6 No 0
PSRC1-002 ENSP00000358920
ENST00000369904
Q6PGN9
Show all »
Show » 310 33.6 No 0
PSRC1-003 ENSP00000474667
ENST00000409138
Q5T2Z0
Show all »
Show » 363 38.8 No 0
PSRC1-005 ENSP00000387791
ENST00000429031
Q5T2Z1
Show all »
Show » 232 25.1 No 0
PSRC1-006 ENSP00000413186
ENST00000418914
205 22.3 No 0
PSRC1-007 ENSP00000474682
ENST00000474126
123 12.5 No 0
PSRC1-009 ENSP00000386323
ENST00000409267
Q6PGN9
Show all »
Show » 333 35.6 No 0
PSRC1-010 ENSP00000358919
ENST00000369903
Q6PGN9
Show all »
Show » 333 35.6 No 0
PSRC1-201 ENSP00000358925
ENST00000369909
Q6PGN9
Show all »
Show » 333 35.6 No 0
PSRC1-202 ENSP00000413591
ENST00000438534
Q6PGN9
Show all »
Show » 363 38.8 No 0