VTCN1

GENE INFORMATION

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Gene name

VTCN1 (HGNC Symbol)

Synonyms

B7-H4, B7H4, B7S1, B7X, FLJ22418

Description

V-set domain containing T cell activation inhibitor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Chromosome

1

Cytoband

p13.1

Chromosome location (bp)

117686209 - 117753556

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134258 (version 75.37)

Entrez gene

79679

UniProt

Q7Z7D3 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z7D3

Antibodypedia

VTCN1 antibodies
 

PROTEIN VIEW

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VTCN1-001
 
VTCN1-002
 
VTCN1-201
 
VTCN1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VTCN1-001 ENSP00000358470
ENST00000369458
Q7Z7D3
Show all »
Show » Show » 282 30.9 No 2
VTCN1-002 ENSP00000351899
ENST00000359008
Q5T2L0
Show all »
Show » Show » 285 31.3 No 2
VTCN1-201 ENSP00000328168
ENST00000328189
Q7Z7D3
Show all »
Show » Show » 166 18.3 No 2
VTCN1-202 ENSP00000444724
ENST00000539893
Q7Z7D3
Show all »
Show » Show » 187 20.7 No 0