YWHAQ

GENE INFORMATION

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Gene name

YWHAQ (HGNC Symbol)

Synonyms

14-3-3, HS1

Description

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide (HGNC Symbol)

Entrez gene summary

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

p25.1

Chromosome location (bp)

9724101 - 9771143

Ensembl

ENSG00000134308 (version 73.37)

Entrez gene

10971

UniProt

P27348 (UniProt - Evidence at protein level)

neXtProt

NX_P27348

Antibodypedia

YWHAQ antibodies
 

PROTEIN VIEW

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YWHAQ-001
 
YWHAQ-002
 
YWHAQ-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

YWHAQ-001 ENSP00000238081
ENST00000238081
P27348
Show all »
Show » 245 27.8 No 0
YWHAQ-002 ENSP00000371267
ENST00000381844
P27348
Show all »
Show » 245 27.8 No 0
YWHAQ-005 ENSP00000398990
ENST00000446619
E9PG15
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Show » 149 17 No 0