ROCK2

GENE INFORMATION

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Gene name

ROCK2

Synonyms

Description

Rho-associated, coiled-coil containing protein kinase 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

p25.1

Chromosome location (bp)

11319887 - 11488456

Ensembl

ENSG00000134318 (version 73.37)

Entrez gene

9475

UniProt

O75116 (UniProt - Evidence at protein level)

neXtProt

NX_O75116

Antibodypedia

ROCK2 antibodies
 

PROTEIN VIEW

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ROCK2-001
 
ROCK2-006
 
ROCK2-007
 
ROCK2-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ROCK2-001 ENSP00000317985
ENST00000315872
O75116
Show all »
Show » Show » 1388 160.9 No 0
ROCK2-006 ENSP00000385509
ENST00000401753
E9PF63
Show all »
Show » Show » 1145 133.3 No 0
ROCK2-007 ENSP00000395957
ENST00000431087
C9JFJ0
Show all »
Show » Show » 203 23.2 No 0
ROCK2-008 ENSP00000261535
ENST00000261535
D6REE7
Show all »
Show » Show » 446 50.7 No 0