FST

GENE INFORMATION

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Gene name

FST (HGNC Symbol)

Synonyms

FS

Description

follistatin (HGNC Symbol)

Entrez gene summary

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

52776239 - 52782964

Ensembl

ENSG00000134363 (version 73.37)

Entrez gene

10468

UniProt

P19883 (UniProt - Evidence at protein level)

neXtProt

NX_P19883

Antibodypedia

FST antibodies
 

PROTEIN VIEW

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FST-001
 
FST-003
 
FST-004
 
FST-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FST-001 ENSP00000256759
ENST00000256759
P19883
Show all »
Show » Show » 344 38 Yes 0
FST-003 ENSP00000380151
ENST00000396947
P19883
Show all »
Show » Show » 317 34.8 Yes 0
FST-004 ENSP00000426315
ENST00000504226
H0YA75
Show all »
Show » 215 23.5 No 0
FST-005 ENSP00000426971
ENST00000497789
Show » 102 10.7 No 0