SLCO1B1

GENE INFORMATION

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Gene name

SLCO1B1 (HGNC Symbol)

Synonyms

LST-1, OATP-C, OATP1B1, SLC21A6

Description

solute carrier organic anion transporter family, member 1B1 (HGNC Symbol)

Entrez gene summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]

Chromosome

12 (Chromosome progress)

Cytoband

p12.1

Chromosome location (bp)

21284136 - 21392180

Ensembl

ENSG00000134538 (version 73.37)

Entrez gene

10599

UniProt

Q9Y6L6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6L6

Antibodypedia

SLCO1B1 antibodies
 

PROTEIN VIEW

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SLCO1B1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLCO1B1-001 ENSP00000256958
ENST00000256958
Q9Y6L6
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