DSG1

GENE INFORMATION

? »

Gene name

DSG1 (HGNC Symbol)

Synonyms

CDHF4, DSG

Description

desmoglein 1 (HGNC Symbol)

Entrez gene summary

Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. [provided by RefSeq, Jul 2008]

Chromosome

18 (Chromosome progress)

Cytoband

q12.1

Chromosome location (bp)

28898052 - 28936992

Ensembl

ENSG00000134760 (version 73.37)

Entrez gene

1828

UniProt

Q02413 (UniProt - Evidence at protein level)

neXtProt

NX_Q02413

Antibodypedia

DSG1 antibodies
 

PROTEIN VIEW

? »
 
 
 
DSG1-001
 
DSG1-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DSG1-001 ENSP00000257192
ENST00000257192
Q02413
Show all »
Show » Show » 1049 113.7 Yes 1
DSG1-002 ENSP00000462666
ENST00000462981
B7Z845
Show all »
Show » 408 42.6 No 0