APLNR

GENE INFORMATION

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Gene name

APLNR (HGNC Symbol)

Synonyms

AGTRL1, APJ, APJR, FLJ90771

Description

apelin receptor (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]

Chromosome

11 (Chromosome progress)

Cytoband

q12.1

Chromosome location (bp)

57001051 - 57004709

Ensembl

ENSG00000134817 (version 73.37)

Entrez gene

187

UniProt

P35414 (UniProt - Evidence at protein level)

neXtProt

NX_P35414

Antibodypedia

APLNR antibodies
 

PROTEIN VIEW

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APLNR-001
 
APLNR-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APLNR-001 ENSP00000257254
ENST00000257254
P35414
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Show » Show » 380 42.7 No 7
APLNR-004 ENSP00000475344
ENST00000606794
Show » Show » 380 42.7 No 7