FADS2

GENE INFORMATION

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Gene name

FADS2 (HGNC Symbol)

Synonyms

D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13

Description

fatty acid desaturase 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Chromosome

11 (Chromosome progress)

Cytoband

q12.2

Chromosome location (bp)

61560452 - 61634826

Ensembl

ENSG00000134824 (version 73.37)

Entrez gene

9415

UniProt

O95864 (UniProt - Evidence at protein level)

neXtProt

NX_O95864

Antibodypedia

FADS2 antibodies
 

PROTEIN VIEW

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 « 
 
FADS2-001
 
FADS2-002
 
FADS2-003
 
FADS2-004
 
FADS2-009
 
FADS2-010
 
FADS2-011
 
FADS2-012
 
FADS2-013
 
FADS2-014
 
FADS2-015
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FADS2-001 ENSP00000257261
ENST00000257261
O95864
Show all »
Show » Show » 422 49.3 Yes 5
FADS2-002 ENSP00000429500
ENST00000522056
B7Z634
Show all »
Show » Show » 413 48.9 No 5
FADS2-003 ENSP00000278840
ENST00000278840
O95864
Show all »
Show » Show » 444 52.3 No 5
FADS2-004 ENSP00000431091
ENST00000521849
O95864
Show all »
Show » Show » 386 45.5 No 5
FADS2-009 ENSP00000430225
ENST00000517312
E5RGD8
Show all »
Show » Show » 93 10.8 No 1
FADS2-010 ENSP00000430054
ENST00000518606
E5RGZ5
Show all »
Show » Show » 103 12.1 No 1
FADS2-011 ENSP00000429693
ENST00000517839
E5RHL3
Show all »
52 6.1 No 0
FADS2-012 ENSP00000428522
ENST00000522639
F5GZU2
Show all »
55 5.9 No 0
FADS2-013 ENSP00000443867
ENST00000521571
F5GZ92
Show all »
Show » 95 11.6 No 2
FADS2-014 ENSP00000437965
ENST00000355484
F5H622
Show all »
Show » Show » 151 18.5 No 2
FADS2-015 ENSP00000458917
ENST00000574708
F5GZU2
Show all »
55 5.9 No 0