C5AR2

GENE INFORMATION

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Gene name

C5AR2 (HGNC Symbol)

Synonyms

C5L2, GPR77

Description

complement component 5a receptor 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Chromosome

19 (Chromosome progress)

Cytoband

q13.32

Chromosome location (bp)

47835404 - 47846606

Ensembl

ENSG00000134830 (version 73.37)

Entrez gene

27202

UniProt

Q9P296 (UniProt - Evidence at protein level)

neXtProt

NX_Q9P296

Antibodypedia

C5AR2 antibodies
 

PROTEIN VIEW

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C5AR2-001
 
C5AR2-002
 
C5AR2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

C5AR2-001 ENSP00000472620
ENST00000595464
Q9P296
Show all »
Show » Show » 337 36.1 No 7
C5AR2-002 ENSP00000471184
ENST00000600626
Q9P296
Show all »
Show » Show » 337 36.1 No 7
C5AR2-201 ENSP00000257267
ENST00000257267
Q9P296
Show all »
Show » Show » 337 36.1 No 7