The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Moderate to strong cytoplasmic positivity, in a few cases combined with membranous staining, was observed in salivary glands, lung, female genitalia, prostate, squamous and respiratory epithelia along with subsets of cells in lymphoid tissues. Cilia in respiratory epithelia and fallopian tube were distinctly stained. Remaining normal tissues were in general negative.
Strong cytoplasmic staining often combined with nuclear and membranous positivity was observed in bone marrow, bladder, placenta, ciliated cells, prostate, female genitalia and squamous epithelia. Remaining normal tissues were generally negative.
Normal tissues showed moderate to strong cytoplasmic and nuclear positivity. Cells of CNS were mostly negative.
The red pulp of spleen, placenta, poietic cells of bone marrow , squamous, urothelial, glandular cells in both genital and respiratory tract showed moderate to strong cytoplasmic and nuclear staining. Remaining normal cells were weakly stained or negative.
Most normal tissues exhibited moderate to strong cytoplasmic and nuclear positivity with additional membranous positivity in respiratory epithelia. Gastrointestinal tract, pancreas, liver, adrenal gland, testis, myocytes and cells in CNS were negative.