ADAM19

GENE INFORMATION

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Gene name

ADAM19 (HGNC Symbol)

Synonyms

MLTNB

Description

ADAM metallopeptidase domain 19 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013]

Chromosome

5 (Chromosome progress)

Cytoband

q33.3

Chromosome location (bp)

156822542 - 157002783

Ensembl

ENSG00000135074 (version 73.37)

Entrez gene

8728

UniProt

Q9H013 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H013

Antibodypedia

ADAM19 antibodies
 

PROTEIN VIEW

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ADAM19-001
 
ADAM19-002
 
ADAM19-003
 
ADAM19-004
 
ADAM19-201
 
ADAM19-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM19-001 ENSP00000257527
ENST00000257527
Q9H013
Show all »
Show » Show » 918 100.8 Yes 1
ADAM19-002 ENSP00000428376
ENST00000517951
E5RIS2
Show all »
Show » 272 31.1 Yes 0
ADAM19-003 ENSP00000428654
ENST00000517905
Q9H013
Show all »
Show » Show » 955 105 Yes 1
ADAM19-004 ENSP00000431027
ENST00000517374
Q8TBU7
Show all »
Show » Show » 489 52.7 No 1
ADAM19-201 ENSP00000377588
ENST00000394020
E7ENW4
Show all »
Show » Show » 920 101 Yes 1
ADAM19-202 ENSP00000414088
ENST00000430702
E9PD32
Show all »
Show » Show » 638 69.3 No 1