HTR1B

GENE INFORMATION

? »

Gene name

HTR1B (HGNC Symbol)

Synonyms

5-HT1B, 5-HT1DB, HTR1D2, S12

Description

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled (HGNC Symbol)

Entrez gene summary

The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM, Oct 2009]

Chromosome

6 (Chromosome progress)

Cytoband

q14.1

Chromosome location (bp)

78171948 - 78173490

Ensembl

ENSG00000135312 (version 73.37)

Entrez gene

3351

UniProt

P28222 (UniProt - Evidence at protein level)

neXtProt

NX_P28222

Antibodypedia

HTR1B antibodies
 

PROTEIN VIEW

? »
 
 
 
HTR1B-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HTR1B-001 ENSP00000358963
ENST00000369947
P28222
Show all »
Show » Show » 390 43.6 No 7