ORC3

GENE INFORMATION

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Gene name

ORC3 (HGNC Symbol)

Synonyms

IMAGE50150, LATHEO, ORC3L

Description

origin recognition complex, subunit 3 (HGNC Symbol)

Entrez gene summary

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

q15

Chromosome location (bp)

88299839 - 88377169

Ensembl

ENSG00000135336 (version 73.37)

Entrez gene

23595

UniProt

Q9UBD5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UBD5

Antibodypedia

ORC3 antibodies
 

PROTEIN VIEW

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ORC3-001
 
ORC3-004
 
ORC3-005
 
ORC3-201
 
ORC3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ORC3-001 ENSP00000376586
ENST00000392844
Q9UBD5
Show all »
Show » Show » 711 82.3 No 0
ORC3-004 ENSP00000257789
ENST00000257789
Q9UBD5
Show all »
Show » Show » 712 82.3 No 0
ORC3-005 ENSP00000475988
ENST00000508875
32 3.7 No 0
ORC3-201 ENSP00000390176
ENST00000417380
B4DZ51
Show all »
Show » Show » 444 51.2 No 0
ORC3-202 ENSP00000444695
ENST00000546266
Q9UBD5
Show all »
Show » Show » 568 65.9 No 0