AMHR2

GENE INFORMATION

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Gene name

AMHR2 (HGNC Symbol)

Synonyms

MISR2, MISRII

Description

anti-Mullerian hormone receptor, type II (HGNC Symbol)

Entrez gene summary

This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]

Chromosome

12 (Chromosome progress)

Cytoband

q13.13

Chromosome location (bp)

53817639 - 53825318

Ensembl

ENSG00000135409 (version 73.37)

Entrez gene

269

UniProt

Q16671 (UniProt - Evidence at protein level)

neXtProt

NX_Q16671

Antibodypedia

AMHR2 antibodies
 

PROTEIN VIEW

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AMHR2-001
 
AMHR2-002
 
AMHR2-003
 
AMHR2-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AMHR2-001 ENSP00000257863
ENST00000257863
Q16671
Show all »
Show » Show » 573 62.7 Yes 1
AMHR2-002 ENSP00000369117
ENST00000379791
Q16671
Show all »
Show » Show » 478 51.8 Yes 1
AMHR2-003 ENSP00000446661
ENST00000550311
Q16671
Show all »
Show » Show » 478 52.2 Yes 1
AMHR2-007 ENSP00000455338
ENST00000550839
H3BPI9
Show all »
Show » 172 19.2 No 0