GDF11

GENE INFORMATION

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Gene name

GDF11 (HGNC Symbol)

Synonyms

BMP-11

Description

growth differentiation factor 11 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq, Jul 2008]

Chromosome

12 (Chromosome progress)

Cytoband

q13.2

Chromosome location (bp)

56137064 - 56150911

Ensembl

ENSG00000135414 (version 73.37)

Entrez gene

10220

UniProt

O95390 (UniProt - Evidence at transcript level)

neXtProt

NX_O95390

Antibodypedia

GDF11 antibodies
 

PROTEIN VIEW

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GDF11-001
 
GDF11-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GDF11-001 ENSP00000257868
ENST00000257868
O95390
Show all »
Show » 407 45.1 Yes 0
GDF11-002 ENSP00000448390
ENST00000546799
Show » 380 42.2 Yes 0