TEC

GENE INFORMATION

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Gene name

TEC (HGNC Symbol)

Synonyms

PSCTK4

Description

tec protein tyrosine kinase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

p11

Chromosome location (bp)

48137800 - 48271881

Ensembl

ENSG00000135605 (version 73.37)

Entrez gene

7006

UniProt

P42680 (UniProt - Evidence at protein level)

neXtProt

NX_P42680

Antibodypedia

TEC antibodies
 

PROTEIN VIEW

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TEC-001
 
TEC-005
 
TEC-015
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TEC-001 ENSP00000370912
ENST00000381501
P42680
Show all »
Show » Show » 631 73.6 No 0
TEC-005 ENSP00000424567
ENST00000505452
D6RB05
Show all »
Show » 100 11.8 No 0
TEC-015 ENSP00000424365
ENST00000515146
D6RB75
Show all »
Show » 51 5.8 No 0