HTR2B

GENE INFORMATION

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Gene name

HTR2B (HGNC Symbol)

Synonyms

5-HT(2B), 5-HT2B

Description

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled (HGNC Symbol)

Entrez gene summary

This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]

Chromosome

2 (Chromosome progress)

Cytoband

q37.1

Chromosome location (bp)

231972944 - 231989832

Ensembl

ENSG00000135914 (version 73.37)

Entrez gene

3357

UniProt

P41595 (UniProt - Evidence at protein level)

neXtProt

NX_P41595

Antibodypedia

HTR2B antibodies
 

PROTEIN VIEW

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HTR2B-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HTR2B-001 ENSP00000258400
ENST00000258400
P41595
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