SERPINE2

GENE INFORMATION

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Gene name

SERPINE2 (HGNC Symbol)

Synonyms

GDN, nexin, PI7, PN1, PNI

Description

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Chromosome

2 (Chromosome progress)

Cytoband

q36.1

Chromosome location (bp)

224839829 - 224904036

Ensembl

ENSG00000135919 (version 73.37)

Entrez gene

5270

UniProt

P07093 (UniProt - Evidence at protein level)

neXtProt

NX_P07093

Antibodypedia

SERPINE2 antibodies
 

PROTEIN VIEW

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SERPINE2-001
 
SERPINE2-002
 
SERPINE2-003
 
SERPINE2-005
 
SERPINE2-007
 
SERPINE2-008
 
SERPINE2-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SERPINE2-001 ENSP00000258405
ENST00000258405
P07093
Show all »
Show » Show » 398 44 Yes 0
SERPINE2-002 ENSP00000386412
ENST00000409304
P07093
Show all »
Show » Show » 397 44 Yes 0
SERPINE2-003 ENSP00000386969
ENST00000409840
P07093
Show all »
Show » Show » 397 44 Yes 0
SERPINE2-005 ENSP00000415786
ENST00000447280
P07093
Show all »
Show » Show » 409 45.3 Yes 0
SERPINE2-007 ENSP00000399655
ENST00000454956
C9K031
Show all »
Show » 87 9.5 Yes 0
SERPINE2-008 ENSP00000408452
ENST00000432738
C9JN98
Show all »
Show » Show » 276 30.5 Yes 0
SERPINE2-009 ENSP00000394518
ENST00000423446
C9JRK5
Show all »
Show » 42 4.7 Yes 0