PLXNC1

GENE INFORMATION

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Gene name

PLXNC1 (HGNC Symbol)

Synonyms

CD232, VESPR

Description

plexin C1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]

Chromosome

12 (Chromosome progress)

Cytoband

q22

Chromosome location (bp)

94542499 - 94701451

Ensembl

ENSG00000136040 (version 73.37)

Entrez gene

10154

UniProt

O60486 (UniProt - Evidence at protein level)

neXtProt

NX_O60486

Antibodypedia

PLXNC1 antibodies
 

PROTEIN VIEW

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PLXNC1-001
 
PLXNC1-002
 
PLXNC1-003
 
PLXNC1-004
 
PLXNC1-005
 
PLXNC1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLXNC1-001 ENSP00000258526
ENST00000258526
O60486
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Show » Show » 1568 175.7 Yes 1
PLXNC1-002 ENSP00000446781
ENST00000549217
F8W1K6
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Show » Show » 416 47.3 No 0
PLXNC1-003 ENSP00000446720
ENST00000547057
B4DHQ7
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Show » Show » 615 70.9 No 0
PLXNC1-004 ENSP00000439225
ENST00000545312
F5H3A2
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Show » 307 35.8 No 0
PLXNC1-005 ENSP00000447625
ENST00000550080
F8W095
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103 11.8 No 0
PLXNC1-006 ENSP00000447843
ENST00000551850
F8VUW4
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Show » 109 12.3 No 0