IGF2BP3

GENE INFORMATION

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Gene name

IGF2BP3 (HGNC Symbol)

Synonyms

CT98, IMP-3

Description

insulin-like growth factor 2 mRNA binding protein 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

p15.3

Chromosome location (bp)

23349828 - 23510086

Ensembl

ENSG00000136231 (version 73.37)

Entrez gene

10643

UniProt

O00425 (UniProt - Evidence at protein level)

neXtProt

NX_O00425

Antibodypedia

IGF2BP3 antibodies
 

PROTEIN VIEW

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IGF2BP3-001
 
IGF2BP3-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IGF2BP3-001 ENSP00000258729
ENST00000258729
O00425
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Show » 579 63.7 No 0
IGF2BP3-004 ENSP00000395936
ENST00000421467
F8WD15
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Show » 81 8.9 No 0