MRPL47

GENE INFORMATION

? »

Gene name

MRPL47 (HGNC Symbol)

Synonyms

CGI-204, NCM1

Description

mitochondrial ribosomal protein L47 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q26.33

Chromosome location (bp)

179306073 - 179322442

Ensembl

ENSG00000136522 (version 73.37)

Entrez gene

57129

UniProt

Q9HD33 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HD33

Antibodypedia

MRPL47 antibodies
 

PROTEIN VIEW

? »
 
 
 
MRPL47-001
 
MRPL47-002
 
MRPL47-003
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL47-001 ENSP00000417602
ENST00000476781
Q9HD33
Show all »
Show » Show » 250 29.5 No 0
MRPL47-002 ENSP00000259038
ENST00000259038
Q9HD33
Show all »
Show » Show » 230 27.1 No 0
MRPL47-003 ENSP00000376427
ENST00000392659
Q9HD33
Show all »
Show » Show » 140 17 No 0