TANK

GENE INFORMATION

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Gene name

TANK (HGNC Symbol)

Synonyms

I-TRAF, TRAF2

Description

TRAF family member-associated NFKB activator (HGNC Symbol)

Entrez gene summary

The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Chromosome

2 (Chromosome progress)

Cytoband

q24.2

Chromosome location (bp)

161993419 - 162092732

Ensembl

ENSG00000136560 (version 73.37)

Entrez gene

10010

UniProt

Q92844 (UniProt - Evidence at protein level)

neXtProt

NX_Q92844

Antibodypedia

TANK antibodies
 

PROTEIN VIEW

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 « 
 
TANK-001
 
TANK-002
 
TANK-003
 
TANK-004
 
TANK-006
 
TANK-008
 
TANK-012
 
TANK-014
 
TANK-015
 
TANK-016
 
TANK-017
 
TANK-020
 
TANK-021
 
TANK-022
 
TANK-023
 
TANK-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TANK-001 ENSP00000259075
ENST00000259075
Q92844
Show all »
Show » 425 47.8 No 0
TANK-002 ENSP00000376505
ENST00000392749
Q92844
Show all »
Show » 425 47.8 No 0
TANK-003 ENSP00000385983
ENST00000403609
Q92844
Show all »
Show » 119 13.6 No 0
TANK-004 ENSP00000385487
ENST00000405852
E7EQA9
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Show » 408 46.2 No 0
TANK-006 ENSP00000399934
ENST00000440506
E7EWR8
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Show » 105 12.2 No 0
TANK-008 ENSP00000384492
ENST00000406287
E7EVA2
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Show » 238 27.5 No 0
TANK-012 ENSP00000392776
ENST00000456358
E7EMT6
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Show » 165 18.8 No 0
TANK-014 ENSP00000384235
ENST00000402568
E7EW82
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239 27.6 No 0
TANK-015 ENSP00000398157
ENST00000432002
E7EV32
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138 15.9 No 0
TANK-016 ENSP00000411041
ENST00000429217
E7ENY2
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190 21.9 No 0
TANK-017 ENSP00000410259
ENST00000441987
E9PEK1
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36 4.2 No 0
TANK-020 ENSP00000387439
ENST00000439442
H7BZ28
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Show » 198 21.8 No 0
TANK-021 ENSP00000412622
ENST00000432692
E7EM55
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Show » 125 14.5 No 0
TANK-022 ENSP00000388930
ENST00000457887
E7ERM9
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Show » 128 14.9 No 0
TANK-023 ENSP00000412556
ENST00000437623
H7C3L4
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275 30.6 No 0
TANK-201 ENSP00000415276
ENST00000457476
Q92844
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Show » 119 13.6 No 0