BLK

GENE INFORMATION

? »

Gene name

BLK (HGNC Symbol)

Synonyms

MGC10442

Description

B lymphoid tyrosine kinase (HGNC Symbol)

Entrez gene summary

This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]

Chromosome

8 (Chromosome progress)

Cytoband

p23.1

Chromosome location (bp)

11351510 - 11422113

Ensembl

ENSG00000136573 (version 73.37)

Entrez gene

640

UniProt

P51451 (UniProt - Evidence at protein level)

neXtProt

NX_P51451

Antibodypedia

BLK antibodies
 

PROTEIN VIEW

? »
 
 
 
BLK-001
 
BLK-004
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BLK-001 ENSP00000259089
ENST00000259089
P51451
Show all »
Show » Show » 505 57.7 No 0
BLK-004 ENSP00000433663
ENST00000529894
E9PJX5
Show all »
Show » Show » 434 49.8 No 0