CFC1

GENE INFORMATION

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Gene name

CFC1 (HGNC Symbol)

Synonyms

CRYPTIC, HTX2

Description

cripto, FRL-1, cryptic family 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Chromosome

2 (Chromosome progress)

Cytoband

q21.1

Chromosome location (bp)

131350339 - 131357123

Ensembl

ENSG00000136698 (version 73.37)

Entrez gene

55997

UniProt

P0CG37 (UniProt - Evidence at protein level)

neXtProt

NX_P0CG37

Antibodypedia

CFC1 antibodies
 

PROTEIN VIEW

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CFC1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CFC1-001 ENSP00000259216
ENST00000259216
P0CG37
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